阿奇霉素

[CAS号] 83905-01-5
[分子量] 748.984
[分子式] C38H72N2O12
[密度] 1.2±0.1 g / cm3
[沸点]在822.1 mmHg下为65.0±760°C
[外观]白色结晶性粉末
[用途]头孢菌素类抗生素
关于阿奇霉素
阿奇霉素是一种大环内酯类抗生素，通常用于治疗细菌感染。
Azithromycin powder is a semi-synthetic, ring-expanded erythromycin, produced by a Beckmann rearrangement of erythromycin oxime and reduction to the imine ether, followed by reductive methylation.阿奇霉素粉末是一种半合成的，扩环的红霉素，由贝克曼重排红霉素肟并还原成亚胺醚，然后进行还原性甲基化反应制得。 Azithromycin was the first of the azalides and was designed to improve stability and biological half-life of erythromycin A, as well as improve activity against Gram negative bacteria.阿奇霉素是第一个氮杂内酯类药物，旨在提高红霉素A的稳定性和生物半衰期，并提高对革兰氏阴性细菌的活性。