牛磺酸

[同义词] 4,4'-亚甲基双（过氢-1,2,4-噻二嗪1,1-二氧化物）;牛磺酸;牛磺酸;
[CAS号] 19388-87-5
[式] C7H16N4O4S2
[分子量] 284.35
[密度] 1.467 g / cm3
[沸点] 471.214°C在760 mmHg
[闪点] 238.782°C 
关于牛磺酸
牛磺酸是具有抗微生物和抗脂多糖特性的活性药物成分（API）。
Taurolidine是一种抗菌剂，用于尝试防止导管感染。 Side effects and the induction of bacterial resistance is uncommon.副作用和诱导细菌耐药性并不常见。 It is also being studied as a treatment for cancer.也正在研究它作为癌症的治疗方法。
It is derived from the endogenous amino acid taurine.它衍生自内源性氨基酸牛磺酸。 Taurolidine's putative mechanism of action is based on a chemical reaction.牛磺酸的推定作用机理是基于化学反应。 During the metabolism of taurolidine to taurinamide and ultimately taurine and water, methylol groups are liberated that chemically react with the mureins in the bacterial cell wall and with the amino and hydroxyl groups of endotoxins and exotoxins.在牛磺酸向牛磺酸酰胺代谢以及最终牛磺酸和水代谢过程中，释放出羟甲基，其与细菌细胞壁中的鼠李糖苷以及内毒素和外毒素的氨基和羟基发生化学反应。 This results in denaturing of the complex polysaccharide and lipopolysaccharide components of the bacterial cell wall and of the endotoxin and in the inactivation of susceptible exotoxins.这导致细菌细胞壁和内毒素的复合多糖和脂多糖成分变性，并导致易感外毒素失活。