柠檬素

Citrinin是一种霉菌毒素,最初从柠檬青霉中分离出来。 It has since been found to be produced by a variety of other fungi which are used in the production of human foods such as grain, cheese, sake and red pigments.此后发现它是由多种其他真菌生产的,这些真菌用于生产人类食品,例如谷物,奶酪,清酒和红色颜料。
柠檬素在所有经过测试的物种中均作为肾毒素,但其急性毒性各不相同,它会引起家畜的霉菌毒素性肾病,并被认为是人类巴尔干肾病和黄米热的病因。
Citrinin is used as a reagent in biological research.柠檬素在生物学研究中用作试剂。 It induces mitochondrial permeability pore opening and inhibits respiration by interfering with complex I of the respiratory chain.它通过干扰呼吸链的复合物I诱导线粒体通透性孔的开放并抑制呼吸。