海沙瑞林

[CAS号] 140703-51-1
[分子式] C47H58N12O6
[分子量] 887.04
[序列] His-D-2-甲基-Trp-Ala-Trp-D-Phe-Lys-NH2
[外观]白色粉末
关于海沙林
Hexarelin是一种合成的生长激素释放肽（GHRP）。
ghrelin类似物Hexarelin（HEX）是一种生长激素促分泌素受体激动剂，一种生长激素释放肽。 Hexarelin可用作内标，用于定量分析（通过色谱法等）禁用的生长激素增强药物，例如GHRP-2。 Hexarelin作为治疗剂的潜在用途促进了对其在体内和体外的生理作用的研究。
Hexarelin是一种六氨基酸的肽。 Studies have shown that hexarelin is actually more effective and longer lasting than growth hormone releasing hormone (GHRH).研究表明，与生长激素释放激素（GHRH）相比，hexarelin实际上更有效且持续时间更长。 It is also known that GHRP-6 has a synergistic effect with GHRH, causing a far greater release than either of these substances alone.还已知GHRP-6具有与GHRH的协同作用，与单独的这些物质中的任一种相比引起更大的释放。 By combining GHRP-1 with Hexarelin, a more potent GH releasing peptide combination is created than ever heard of.通过将GHRP-6与Hexarelin结合，可以产生比以往更有效的GH释放肽组合。 The potential clinical usefulness of these GH releasing hexapeptides is also reinforced by observations that long-term administration produces elevations in circulating IGF-1 concentrations.这些观察到的GH释放六肽的潜在临床实用性也因长期服用会使循环IGF-3浓度升高而得到加强。 Long-term treatment with GHRP-XNUMX similarly has been shown to elevate serum IGF-XNUMX as well as IGF-binding protein-XNUMX concentrations and promote linear growth.长期使用GHRP-XNUMX进行治疗已显示出可升高血清IGF-XNUMX和IGF结合蛋白XNUMX的浓度并促进线性生长。